Case Report: Intestinal Obstruction in a Patient on Antiplatelet Therapy
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Abstract
Background Antiplatelet therapy is commonly prescribed for various cardiovascular conditions, but it represents a unique challenge in dealing with surgical emergencies, such as intestinal obstruction. Our case is a 47-year-old patient who had a history of CABG and was on maintenance dual antiplatelet therapy, "Aspirin and Clopidogrel", attended the ER with a short history of acute abdominal pain associated with vomiting and distension. Clinical findings and imaging studiesrevealed features of intestinal obstruction.
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Sandner S, Redfors B, Gaudino M. Antiplatelet therapy around CABG: the latest evidence. Curr Opin Cardiol. 2023 Nov 1;38(6):484-489. Epub 2023 Sep 21. PMID: 37751394; PMCID: PMC10552805. DOI: https://doi.org/10.1097/HCO.0000000000001078
Kim SH, Han K, Kang G, Lee SW, Park CM, Cho J, Choi JW, Park SJ, Kang M, Kim TJ, Hong SH, Kwon YC, Park J, Shin D. Risk of Postoperative Gastrointestinal Bleeding and Its Associated Factors: A Nationwide Population-Based Study in Korea. J Pers Med. 2021 Nov 18;11(11):1222. PMID: 34834574; PMCID: PMC8621831. DOI: https://doi.org/10.3390/jpm11111222
Small Bowel Obstruction, Bower, Katie Love et al, Surgical Clinics, Volume 98, Issue 5, 945 – 971,2018. DOI: https://doi.org/10.1016/j.suc.2018.05.007
Edwards MK, Kuppler CS, Croft CA, Eason-Bates HM. Adhesive Closed-loop Small Bowel Obstruction. Clin Pract Cases Emerg Med. 2018 Jan 9;2(1):31-34. PMID: 29849259; PMCID: PMC5965135. DOI: https://doi.org/10.5811/cpcem.2017.10.35927
Kang DY, Lee SH, Lee SW, et al. Aspirin Monotherapy Versus No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low- to Intermediate-Risk Noncardiac Surgery. J Am Coll Cardiol 2024; 84:2380-2389. DOI: https://doi.org/10.1016/j.jacc.2024.08.024
Hébert J, Eltonsy S, Gaudet J, Jose C. Incidence and risk factors for anastomotic bleeding in lower gastrointestinal surgery. BMC Res Notes. 2019 Jul 3;12(1):378. PMID: 31269980; PMCID: PMC6607592. DOI: https://doi.org/10.1186/s13104-019-4403-0
Ryou SH, Bang KB. Endoscopic management of postoperative bleeding. Clin Endosc. 2023;56(6):706-715. DOI: https://doi.org/10.5946/ce.2023.028
Jung K, Moon W. Role of endoscopy in acute gastrointestinal bleeding in real clinical practice: An evidence-based review. World J Gastrointest Endosc. 2019 Feb 16;11(2):68-83. PMID: 30788026; PMCID: PMC6379746. DOI: https://doi.org/10.4253/wjge.v11.i2.68
Po-Lin Lee, Kai-Suan Yang, Hong-Wei Tsai, Sen-Kuang Hou, Yi-No Kang, Chun-Chao Chang, Tranexamic acid for gastrointestinal Bleeding: A systematic review with Meta-analysis of randomized clinical trials, The American Journal of Emergency Medicine, Volume 45,2021, Pages 269-279, ISSN 0735-6757. DOI: https://doi.org/10.1016/j.ajem.2020.08.062
Klaassen RA, Selles CA, van den Berg JW, Poelman MM, van der Harst E., Tranexamic acid therapy for Postoperative bleeding after bariatric surgery. BMC Obes. 2018 Dec 3;5:36. PMID: 30524741; PMCID: PMC6276262. DOI: https://doi.org/10.1186/s40608-018-0213-5
Banerjee, S., Angiolillo, D., Boden, W. et al. Use of Antiplatelet Therapy/DAPT for Post-PCI Patients Undergoing Noncardiac Surgery. JACC. 2017 Apr, 69 (14) 1861–1870. DOI: https://doi.org/10.1016/j.jacc.2017.02.012
Madyarov V, Kuzikeev M, Malgazhdarov M, Abzalbek Y, Zhapbarkulova G. Causes of adverse outcomes in acute intestinal obstruction. Journal of Complementary and Integrative Medicine. 2023;20(4): 788-796. DOI: https://doi.org/10.1515/jcim-2023-0189
Ali, A., Mohamed, Y., AN, M., & Güler, İ. (2024). Etiology, Clinical Manifestations, and Imaging Evaluation of Intestinal Obstruction in Adults at Tertiary Hospital in Mogadishu, Somalia: A Retrospective Study. International Journal of General Medicine, 17(), 5563-5572.