Analysis of Charge Variant Profiles in Antibody Conjugates
Article Sidebar
Main Article Content
Abstract
The aim
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
How to Cite
References
Isbera, M., Abbood, A., & Ibrahim, W. (2016). Weight and Content Uniformity of Warfarin Sodium Half Tablets. Research Journal of Pharmacy and Technology, 9(3):215-218. DOI: https://doi.org/10.5958/0974-360X.2016.00039.1.
Abbood, A., & Layka, R. (2017). Weight and content uniformity Study of captopril half-tablets. Research Journal of Pharmacy and Technology, 10(6):1621-1626. DOI: https://doi.org/10.5958/0974-360X.2017.00285.2.
Chbani D, Abbood A, & Alkhayer M. (2018). Determination of Nitrite and Nitrate Ions levels in some types of processed meats marketed locally. Research Journal of Pharmacy and Technology, 11(4):1442-1447. DOI: https://doi.org/10.5958/0974-360X.2018.00269.X.
Abbood, A., Malek, Z., Al-Homsh, Y, & Thallaj, N. (2022). In vitro Study for Antibiotic resistance of bacteria causing Urinary Tract Infection from Syrian adults. Research Journal of Pharmacy and Technology, 15(10):4727-2. DOI: https://doi.org/10.52711/0974-360X.2022.00794.
Abbood, A., Malek, Z., & Thallaj, N. (2022). Antibiotic resistance of urinary tract pathogens in Syrian children. Research Journal of Pharmacy and Technology, 15(11):4935-9. DOI: https://doi.org/10.52711/0974-360X.2022.00829.
Abbood, A. (2018). Determination of phenolic content and antioxidant activity of some cosmetic creams available in the Syrian market. Journal of Chemical and Pharmaceutical Sciences, 11:280-3. DOI: https://doi.org/10.30558/jchps.20181104006.
Zrekah, G.H., Diab, D.A., Abboud, A. (2016). Determination of Protein and fat oxidation levels in imported infant formula available in Syria. International Journal of Pharmacy and Pharmaceutical Sciences, 8:169-72. https://journals.innovareacademics.in/index.php/ijpps/article/view/9899.
Abbood, A. (2023). Optimization of the Imaged cIEF Method for Monitoring the Charge Heterogeneity of Antibody-Maytansine Conjugate, Journal of Analytical Methods in Chemistry, Article ID 8150143, 10 pages. DOI: https://doi.org/10.1155/2023/8150143.
Abbood, A. (2024). Study of formulation effects on the charge variant profile of antibody-maytansine conjugates by icIEF method. Acta Pharm. Sci, 62 (2): 288-300. https://www.actapharmsci.com/abstract.php?id=872
Thallaj, N. (2024). Advancements in Pharmaceutical Science: Synthesis and Application of Molecular Cages Integrating N-Heterocyclic Carbenes for Enhanced Stability and Functionality. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-5 Issue-1, pages 6-19. DOI: https://doi.org/10.54105/ijapsr.A4063.05011224.
Abbood, A. (2024). Monitoring the charge variant profile of antibody-tomaymycin conjugates by icIEF method, Acta Pharm. Sci, 62 (1), 226-239. https://actapharmsci.com/uploads/pdf/pdf_868.pdf
Abbood, A., Herrenknecht, C., Proczek, G., Descroix, S., Rodrigo, J., Taverna, M., & Smadja, C. (2011). Hexylacrylate-based mixed-mode monolith, a stationary phase for the nano-HPLC separation of structurally related enkephalins. Analytical and bioanalytical chemistry, 400(2), 459–468. DOI: https://doi.org/10.1007/s00216-011-4762-4.
Asaad, R.A. & Abdullah, S.S. (2018). Breast Cancer Subtypes (BCSs) Classification according to Hormone Receptor Status: Identification of Patients at High Risk in Jableh- Syria. Research Research Journal of Pharmacy and Technology, 11(8): 3703-3710. DOI: https://doi.org/10.5958/0974-360X.2018.00680.7.
Asaad, R.A. (2017). Hormone Receptor Status and its Relation to C-Reactive Protein and other Prognostic factors in Breast Cancer in Jableh- Syria. Research Journal of Pharmacy and Technology, 10(9):3003-3010. DOI: http://doi.org/10.5958/0974-360X.2017.00532.7
Labban, L., & Thallaj, N. (2019). The Effect of Magnesium Supplementation on Hba1c Level and Lipid Profile Among Type 2 Diabetics. Acta Scientific Nutritional Health, 3,10, 7-12. DOI: https://doi.org/10.31080/ASNH.2019.03.0435.
Labban, L., Thallaj, N., & Malek, Z. (2019). The implications of E-cigarettes or" vaping" on the nutritional status. Journal of Medical Research and Health Sciences, 2, 11, 784-787. https://jmrhs.info/index.php/jmrhs/article/view/128
Labban, L., Thallaj, N., & Labban, A. (2020). Assessing the Level of Awareness and Knowledge of COVID-19 Pandemic among Syrians. Archives of Medicine, 12, 2:8, 1-5. DOI: https://doi.org/10.36648/1989-5216.12.3.309
Morkus, R., &Abbood, A. (2024). A Survey of the Awareness and Practices of Antibiotic Use Among College Undergraduates and Graduates in Latakia. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-3, pp: 1-6. DOI: https://doi.org/10.54105/ijapsr.C4039.04030424
Machkour, A., Thallaj, N.K., Benhamou, L., Lachkar, M., & Mandon, D. (2006). The Coordination Chemistry of FeCl3 and FeCl2 to Bis [2‐(2, 3‐dihydroxyphenyl)‐6‐pyridylmethyl](2‐pyridylmethyl) amine: Access to a Diiron (iii) Compound with an Unusual Pentagonal‐Bipyramidal/Square‐Pyramidal Environment Chemistry–A European Journal, 25;12(25): 6660-6668. DOI: https://doi.org/10.1002/chem.200600276
Thallaj, N.K., Rotthaus, O., Benhamou, L., Humbert, N., Elhabiri, M., Lachkar, M., Welter, R., Albrecht-Gary, A.M., & Mandon, D. (200). Chemistry. 14(22):6742-53.P6745-6746-6747. DOI: https://doi.org/10.1002/chem.200701967
Thallaj, N.K., Przybilla, J., Welter, R., & Mandon, D. (2008). A ferrous center as a reaction site for hydration of a nitrile group into a carboxamide in mild conditions. J. Am. Chem. Soc, 130, 2414-2415. DOI: https://doi.org/10.1021/ja710560g.
Thallaj, N. (2022). Microwave-Assisted Synthesis of Oxadiazole and Thiazolidine Derivatives. Indian Journal of Advanced Chemistry, 1, 3, 2022. 10-14. DOI: https://doi.org/10.54105/ijac.d2015.102222.
Thallaj, N. (2022). Quick Review of Chemistry Related to the [Fe]- Hydrogenases. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), 2,4, 1-15. DOI: https://doi.org/10.54105/ijapsr.C4016.062422.
Thallaj, N. (2022). A Short Review of Some Examples of the Binding of Fullerenes C60 to Transition Metal Complexes. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), 2, 6, 1-12. DOI: https://doi.org/10.54105/ijapsr.C4015.102622.
Thallaj, N. (2023). Review of a Few Selected Examples of Intermolecular Dioxygenases Involving Molecular Oxygen and Non-Heme Iron Proteins. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR). 3, 2, 1-18. DOI: https://doi.org/10.54105/ijapsr.C4011.023223.
Thallaj, N. (2023). A Brief Overview of the General Characteristics and Reactivity Towards Dioxygen of the Ferrous Tris (2-Pyridylmethyl Amine) Series Complexes is Presented. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR). 3, 3, 1-18. DOI: https://doi.org/10.54105/ijapsr.C4012.043323.
Labban, L. , Kudsi, M., Malek, Z., & Thallaj, N. (2020). Advances in Medical, Dental and Health Sciences, 3, 3,45-48. DOI: https://doi.org/10.5530/amdhs.2020.3.11
Thallaj, N. (2024). Detecting Antioxidant Behavior for Phenolic Content of Some Beauty Care Creams in Syrian Market. Indian Journal of Advanced Chemistry, vol. 2, no. 1, pp. 10–14. DOI: https://doi.org/10.54105/ijac.C2013.041322.
Thallaj, N.K., Mandon, D., & White, K.A. (2007). The Design of Metal Chelates with a Biologically Related Redox‐Active Part: Conjugation of Riboflavin to Bis (2‐pyridylmethyl) amine Ligand and Preparation of a Ferric Complex Eur. J. of Inorg. Chem., 44–47. DOI: https://doi.org/10.1002/ejic.200600789
Thallaj, N.K., Orain, P.Y., Thibon, A., Sandroni, M., Welter. R, & Mandon, D. (2014). Steric Congestion at, and Proximity to, a Ferrous Center Leads to Hydration of α-Nitrile Substituents Forming Coordinated Carboxamides. Inorg Chem, 4;53(15):7824-36. DOI: https://doi.org/10.1021/ic500096h
Wane, A., Thallaj, N.K., & Mandon, D. (2008). The Reactivity of Molecular Dioxygen on a Series of Isostructural Dichloroferrous Complexes with Tripodal Tetraamine Ligands: General Access to µ-oxo Diferric Complexes, and Effect of α-Fluorination on the Kinetics of
the Reaction. Chemistry A European Journal, 14 (22), 6742-6753. DOI: https://doi.org/10.1002/chem.200701967
Besher, S., Alallan, L., Hasan, M.I., Alshamaa, I., & Thallaj, N. (2024). Influence of Soil Salinity on the Chemical Composition of Essential Oil of Rosmarinus officinalis in Syria. Research Journal of Pharmacy and Technology, 17(5):2282-8. DOI: http://doi.org/10.52711/0974-360X.2024.00358.
Khatib, O., Alshimale, T., Alsaadi, A., & Thallaj, N. (2024). The Global Impact of HIV: A Comprehensive Review. IJAPSR, vol. 4, no. 3, pp. 6–19,.DOI: https://doi.org/10.54105/ijapsr.C4040.04030424
Salloum, R., Baddour, F., & Abbood, A. (2024). A Questionnaire to Evaluate Undergraduate Students’ Consumption and Awareness of Non-Steroidal Anti-Inflammatory Drugs in Syria. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-4, pages 1-6. DOI: https://doi.org/10.54105/ijapsr.C4041.04040624.
Zanboua, R., & Abbood, A. (2024). Survey of Knowledge About the Interaction Between Food and Drugs Among the Syrian Population. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-4, pages 22-28. DOI: https://doi.org/10.54105/ijapsr.D4044.04040624.
Mahfouz, H., Assaf, A., & Abbood, A. (2024). Survey of Usage and Awareness of Ibuprofen Among the Syrian Population. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-5, pages 23-28. DOI: https://doi.org/10.54105/ijapsr.E4048.04050824.
Antakly, R., Najjar, F., & Abbood, A. (2024). Statistical Overview of Drug Shortage in Syria. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-5 Issue-1, pages 1-5. DOI: https://doi.org/10.54105/ijapsr.A4059.05011224.
Abbood, A. (2024). Insights into Therapeutic Peptides and their Quality Control. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-5 Issue-1, pages 16-27. DOI: https://doi.org/10.54105/ijapsr.A4059.05011224.
Abbood A. Overview of Analytical Methods for Characterizing the Charge Heterogeneity of Antibody-Drug Conjugates. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-5, August 2024, pages 16-22. DOI: https://doi.org/10.54105/ijapsr.E4047.04050824.
Nouira, R., & Abbood, A. (2024). Assessment of Knowledge About High Blood Pressure Among Syrians. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-6, pages 28-32. DOI: https://doi.org/10.54105/ijapsr.F4053.04061024.
Malek, Z., Abbood, A., & Thallaj, N. (2022). "Xi'an ShiyouDaxueXuebao (ZiranKexue Ban)." Journal of Xi'an Shiyou University, Natural Sciences, 302-312. DOI: https://doi.org/10.17605/OSF.10/K56XY.
Al-Saroukhy, R., Al-Kara, R., Habib, R., & Abbood, A. (2024). Assessment of use and Awareness of Diclofenac in Syria. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), Volume-4 Issue-6, pages 1-6. DOI: https://doi.org/10.54105/ijapsr.F4052.04061024.
Asaad, R.A. (2023). The association between Triglyceride-Glucose index and Hypertension status (stages and phenotypes) in Type II Diabetes Mellitus. Research Journal of Pharmacy and Technology, 16(6): 2963-2968. DOI: https://doi.org/10.52711/0974-360X.2023.00489
Asaad, R.A. (2022). Evaluation of adiposity phenotypes: lipid accumulation product index, visceral adipose index, and body roundness index as predictor markers for metabolic syndrome development in type 2 diabetes mellitus. Bulletin of Pharmaceutical Sciences. Assiut, 45(2): 097-1107. DOI: https://doi.org/10.21608/bfsa.2022.149592.1423.
Asaad, R.A. (2018). Lymph Node Ratio (LNR) as a predictive factor in addition to pNstaging in Syrian-breast cancer patients at diagnosis. Research Journal of Pharmacy and Technology. 11(3):933-940. DOI: https://doi.org/10.5958/0974-360X.2018.00173.7.
Asaad, R.A. (2023). Relative Fat Mass (RFM) Evaluates the Whole Body Fat (WBF) and predicts Cardio-metabolic Disorders as a new obesity marker in Syrian-population. Research Journal of Pharmacy and Technology, 16(9):4399-5. DOI: https://doi.org/10.52711/0974-360X.2023.00719.
Malek, Z.S., Sagem D., Pevet, P., & Raison, S. (2007). Endocrinology, 148 (11), 5165-5173. DOI: https://doi.org/10.1210/en.2007-0526.
Qattan, M., Dashash, M., & Malek, Z. (2024). Enhancing Academic Success: A mixed Study on the Influencing Factors among Pharmacy Students in Syrian Universities. F1000Res. 11;13:868. DOI: https://doi.org/10.12688/f1000research.151218.2.
Thallaj, N. (2022). Design and Synthesis Ligands Tetradents Substituted with Halogenes in α- Position and Conjugation with Riboflavin (Bioconjugates): Conjugate ligands Type TPA’s with Flavonoids as un Electron Mediator. Biomedicine and Chemical Sciences, 1(2), 47–56. DOI: https://doi.org/10.48112/bcs.v1i2.85.
Thallaj, N., Alrasho, J. F., & Sofi, F. K. (2024). Advancements in Antiviral Therapeutics: A Comprehensive Review of Hepatitis C Virus and Novel Flavone Leads. International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), 5(1), 28-40. DOI: https://doi.org/10.54105/ijapsr.A4064.05011224.
Thallaj, N. (2023). International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR) 2023. 3, 3,1-10. DOI: https://doi.org/10.54105/ijapsr.C4012.043323
Thallaj, N. (2024). International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR), 4, 1,32-52. DOI: https://doi.org/10.54105/ijapsr.A4036.124123.
Thallaj, N. (2022). Xi'an ShiyouDaxueXuebao (ZiranKexue Ban)/ Journal of Xi'an Shiyou University, Natural Sciences Edition, 65, 06. 289-301. DOI: https://doi.org/10.17605/OSF.IO/W8RS5.
Thallaj, N. (2022). Xi'an ShiyouDaxueXuebao (ZiranKexue Ban)/ Journal of Xi'an Shiyou University, Natural Sciences Edition, 65, 06. 313-328. DOI: https://doi.org/10.17605/OSF.IO/K8RFE
Thallaj, N. (2022). Xi'an Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of Xi'an Shiyou University, Natural Sciences Edition, 65, 7, 169-184. DOI: https://doi.org/10.17605/OSF.IO/7F23D
Malek, Z. (2022). Xi'an Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of Xi'an Shiyou University, Natural Sciences Edition, 65, 7, 143-152. DOI: https://doi.org/10.17605/OSF.IO/2UNHK.
Thallaj, N. (2022). Xi'an Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of Xi'an Shiyou University, Natural Sciences Edition, 65, 7, 110-142. DOI: https://doi.org/10.17605/OSF.IO/KZRDJ.
Thallaj, N. (2022). Indian journal of advanced chemistry, 2, 1, 10-14. DOI: https://doi.org/10.54105/ijac.C2013.041322
Park, H. (2022). The Simplest Pharmacokinetic Equation in ADC (Antibody Drug Conjugate) or PDC (Peptide Drug Conjugate) Research. In International Journal of Advanced Pharmaceutical Sciences and Research (Vol. 2, Issue 5, pp. 1–4). DOI: https://doi.org/10.54105/ijapsr.c4017.082522
Biswas, R., Roy, S., & Biswas, A. (2019). Mammogram Classification using Curvelet Coefficients and Gray Level Co-Occurrence Matrix for Detection of Breast Cancer. In International Journal of Innovative Technology and Exploring Engineering (Vol. 8, Issue 12, pp. 4819–4824). DOI: https://doi.org/10.35940/ijitee.l3694.1081219